Iodized Oil: Its Role in the Management of Iodine Deficiency Disorders


F Azizi 1 , *

1 Endocrine Research Center, Research Institute for Endocrine Sciences, Shaheed Beheshti University of Medical Sciences, [email protected], I.R.Iran

How to Cite: Azizi F. Iodized Oil: Its Role in the Management of Iodine Deficiency Disorders, Int J Endocrinol Metab. Online ahead of Print ; 5(2):91-98.


International Journal of Endocrinology and Metabolism: 5 (2); 91-98
Article Type: Review Article
Received: June 16, 2006
Accepted: April 20, 2006


Although universal salt iodization has been used as the most effective method of providing iodine sup-plementation, in areas where salt iodization program has failed, or when iodized salt is not widely avail-able, iodized oil can be used for iodine supplemen-tation. Following administration of iodized oil, io-dine is continuously released from the lipid stores over long periods of time. The effect may last for one year after oral and up to 3-7 years after intramuscular administration, helping to prevent endemic goiter, physical and psychomotor retardation, and the un-desirable pre- and postnatal complications of iodine deficiency. Iodized oil administration decreases the size of goiter, reverses hypothyroidism, improves psychomotor performance and corrects auditory dis-turbances caused by iodine deficiency. Derma-tologic complications, iodine induced hyperthyroid-ism and hypothyroidism may occur following its use, but enhancement of thyroid autoimmunity and thyroiditis have rarely been reported. The use of io-dized oil during pregnancy has no deleterious ef-fects on the thyroid function of the offspring.

© 0, International Journal of Endocrinology and Metabolism. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

Full Text

Full text is available in PDF