International Journal of Endocrinology and Metabolism

Published by: Kowsar

Evidence-Based and Patient-Oriented Inositol Treatment in Polycystic Ovary Syndrome: Changing the Perspective of the Disease

Antonio Simone Laganà 1 , * , Paola Rossetti 2 , Fabrizio Sapia 3 , Benito Chiofalo 1 , Massimo Buscema 2 , Gaetano Valenti 3 , Agnese Maria Chiara Rapisarda 3 and Salvatore Giovanni Vitale 1
Authors Information
1 Unit of Gynecology and Obstetrics, Department of Human Pathology in Adulthood and Childhood “G. Barresi”, University of Messina, Messina, Italy
2 Unit of Diabetology and Endocrino-Metabolic Diseases, Hospital for Emergency Cannizzaro, Catania, Italy
3 Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy
Article information
  • International Journal of Endocrinology and Metabolism: January 2017, 15 (1); e13272
  • Published Online: January 22, 2017
  • Article Type: Editorial
  • Received: November 9, 2016
  • Revised: January 2, 2017
  • Accepted: January 14, 2017
  • DOI: 10.5812/ijem.43695

To Cite: Laganà A S, Rossetti P, Sapia F, Chiofalo B, Buscema M, et al. Evidence-Based and Patient-Oriented Inositol Treatment in Polycystic Ovary Syndrome: Changing the Perspective of the Disease, Int J Endocrinol Metab. 2017 ; 15(1):e13272. doi: 10.5812/ijem.43695.

Copyright © 2017, Research Institute For Endocrine Sciences and Iran Endocrine Society. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. The Rationale of Inositol Therapy in Polycystic Ovary Syndrome
2. Overview of Clinical Studies
3. Conclusion
  • 1. Laganà AS, Rossetti P, Buscema M, La Vignera S, Condorelli RA, Gullo G, et al. Metabolism and Ovarian Function in PCOS Women: A Therapeutic Approach with Inositols. Int J Endocrinol. 2016; 2016: 6306410[DOI][PubMed]
  • 2. Muscogiuri G, Palomba S, Laganà AS, Orio F. Current Insights about Inositol Isoforms, Mediterranean and Ketogenic Diets for Polycystic Ovary Syndrome: From Bench to Beside. Curr Pharm Des. 2016; 22(36): 5554-7[DOI]
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  • 8. Tang T, Lord JM, Norman RJ, Yasmin E, Balen AH. Insulin-sensitising drugs (metformin, rosiglitazone, pioglitazone, D-chiro-inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility. Cochrane Database Syst Rev. 2012; (5): 3053[DOI][PubMed]
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