International Journal of Endocrinology and Metabolism

Published by: Kowsar

Plasma Acylated Ghrelin Response to One Session Circuit Resistance Exercise in Fasted and High Carbohydrate Meal in Healthy Young Men

Marzyeh Saghebjoo 1 , Mehdi Hedayati 2 , * , Yadgar Fahimi 1 and Saeed Ilbeigi 1
Authors Information
1 Faculty of Physical Education and Sport Sciences, University of Birjand, Birjand, IR Iran
2 Cellular and Molecular Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran
Article information
  • International Journal of Endocrinology and Metabolism: October 01, 2013, 11 (4); e8568
  • Published Online: October 1, 2013
  • Article Type: Research Article
  • Received: October 13, 2012
  • Revised: June 1, 2013
  • Accepted: June 9, 2013
  • DOI: 10.5812/ijem.8568

To Cite: Saghebjoo M, Hedayati M, Fahimi Y, Ilbeigi S. Plasma Acylated Ghrelin Response to One Session Circuit Resistance Exercise in Fasted and High Carbohydrate Meal in Healthy Young Men, Int J Endocrinol Metab. 2013 ; 11(4):e8568. doi: 10.5812/ijem.8568.

Copyright © 2013, Research Institute For Endocrine Sciences and Iran Endocrine Society. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature. 1999; 402(6762): 656-60[DOI][PubMed]
  • 2. Saghebjoo M, Ghanbari-Niaki A, Rajabi H, Fathi R, Hedayati M. [Effects of circuit resistance training on plasma ghrelin levels in young women. Iranian Journal of Endorinology and Metabolism]. 2011; 12: 529-35
  • 3. Wynne K, Stanley S, McGowan B, Bloom S. Appetite control. J Endocrinol. 2005; 184(2): 291-318[DOI][PubMed]
  • 4. Speakman JR. Obesity: the integrated roles of environment and genetics. J Nutr. 2004; 134(8 Suppl): 2090S-2105S[PubMed]
  • 5. Hedayati M, Saghebjoo M, Ghanbari-Niaki A. Effects of circuit resistance training intensity on the plasma ghrelin to obestatin ratios in healthy young women. Int J Endocrinol Metab. 2012; 10(2): 475-9[DOI][PubMed]
  • 6. Kojima M, Hosoda H, Matsuo H, Kangawa K. Ghrelin: discovery of the natural endogenous ligand for the growth hormone secretagogue receptor. Trends Endocrinol Metab. 2001; 12(3): 118-22[PubMed]
  • 7. Hosoda H, Kojima M, Mizushima T, Shimizu S, Kangawa K. Structural divergence of human ghrelin. Identification of multiple ghrelin-derived molecules produced by post-translational processing. J Biol Chem. 2003; 278(1): 64-70[DOI][PubMed]
  • 8. Bang AS, Soule SG, Yandle TG, Richards AM, Pemberton CJ. Characterisation of proghrelin peptides in mammalian tissue and plasma. J Endocrinol. 2007; 192(2): 313-23[DOI][PubMed]
  • 9. Moran LJ, Luscombe-Marsh ND, Noakes M, Wittert GA, Keogh JB, Clifton PM. The satiating effect of dietary protein is unrelated to postprandial ghrelin secretion. J Clin Endocrinol Metab. 2005; 90(9): 5205-11[DOI][PubMed]
  • 10. Mirzaei B, Irandoust K, Rahmani-Nia F, Mohebbi H, Hassan-Nia S. Unacylated ghrelin levels increase after aerobic exercise in obese women. Brazilian J Biomotric. 2009; 3(1): 11-20
  • 11. Zwirska-Korczala K, Konturek SJ, Sodowski M, Wylezol M, Kuka D, Sowa P, et al. Basal and postprandial plasma levels of PYY, ghrelin, cholecystokinin, gastrin and insulin in women with moderate and morbid obesity and metabolic syndrome. J Physiol Pharmacol. 2007; 58 Suppl 1: 13-35[PubMed]
  • 12. Soriano-Guillen L, Barrios V, Martos G, Chowen JA, Campos-Barros A, Argente J. Effect of oral glucose administration on ghrelin levels in obese children. Eur J Endocrinol. 2004; 151(1): 119-21[PubMed]
  • 13. Tschop M, Smiley DL, Heiman ML. Ghrelin induces adiposity in rodents. Nature. 2000; 407(6806): 908-13[DOI][PubMed]
  • 14. Tannous dit El Khoury D, Obeid O, Azar ST, Hwalla N. Variations in postprandial ghrelin status following ingestion of high-carbohydrate, high-fat, and high-protein meals in males. Ann Nutr Metab. 2006; 50(3): 260-9[DOI][PubMed]
  • 15. Kraemer RR, Castracane VD. Exercise and humoral mediators of peripheral energy balance: ghrelin and adiponectin. Exp Biol Med (Maywood). 2007; 232(2): 184-94[PubMed]
  • 16. Hamedinia M, Davarzani Z, Hosseini kakhk A. [The effect of one session of swimming and running training on hunger rate and ghrelin, insulin and cortisol hormones of the plasma in the healthy girls]. Iran J Endorinol and Metab. 2011; 13: 82-9
  • 17. Ballard TP, Melby CL, Camus H, Cianciulli M, Pitts J, Schmidt S, et al. Effect of resistance exercise, with or without carbohydrate supplementation, on plasma ghrelin concentrations and postexercise hunger and food intake. Metabolism. 2009; 58(8): 1191-9[DOI][PubMed]
  • 18. Brzycki M. Strength testing—predicting a one-rep max from reps-to-fatigue. JOPERD. 1993; 64(1): 88-90
  • 19. Harris JA, Benedict FG. A Biometric Study of Basal Metabolism in Man. 1919;
  • 20. Foster-Schubert KE, Overduin J, Prudom CE, Liu J, Callahan HS, Gaylinn BD, et al. Acyl and total ghrelin are suppressed strongly by ingested proteins, weakly by lipids, and biphasically by carbohydrates. J Clin Endocrinol Metab. 2008; 93(5): 1971-9[DOI][PubMed]
  • 21. Sauseng W, Nagel B, Gamillscheg A, Aigner R, Borkenstein M, Zotter H. Acylated ghrelin increases after controlled short-time exercise in school-aged children. Scand J Med Sci Sports. 2011; 21(6)-5[DOI][PubMed]
  • 22. Ghanbari-Niaki A. Ghrelin and glucoregulatory hormone responses to a single circuit resistance exercise in male college students. Clin Biochem. 2006; 39(10): 966-70[DOI][PubMed]
  • 23. Di Francesco V, Fantin F, Residori L, Bissoli L, Micciolo R, Zivelonghi A, et al. Effect of age on the dynamics of acylated ghrelin in fasting conditions and in response to a meal. J Am Geriatr Soc. 2008; 56(7): 1369-70[DOI][PubMed]
  • 24. Volek JS. Influence of nutrition on responses to resistance training. Med Sci Sports Exerc. 2004; 36(4): 689-96[PubMed]
  • 25. Tesauro M, Schinzari F, Caramanti M, Lauro R, Cardillo C. Metabolic and cardiovascular effects of ghrelin. Int J Pept. 2010; 2010[DOI][PubMed]
  • 26. Blom WA, Lluch A, Stafleu A, Vinoy S, Holst JJ, Schaafsma G, et al. Effect of a high-protein breakfast on the postprandial ghrelin response. Am J Clin Nutr. 2006; 83(2): 211-20[PubMed]
  • 27. Wilmore JH, Costill DL. Physiology of sports and exercise. 1994;
  • 28. Few JD. Effect of exercise on the secretion and metabolism of cortisol in man. J Endocrinol. 1974; 62(2): 341-53[PubMed]
  • 29. Horvath TL, Diano S, Sotonyi P, Heiman M, Tschop M. Minireview: ghrelin and the regulation of energy balance--a hypothalamic perspective. Endocrinology. 2001; 142(10): 4163-9[PubMed]
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