International Journal of Endocrinology and Metabolism

Published by: Kowsar

Radioiodine Contamination Artifacts and Unusual Patterns of Accumulation in Whole-body I-131 Imaging: A Case Series

Pelin Ozcan Kara 1 , * , Emel Ceylan Gunay 1 and Alihan Erdogan 1
Authors Information
1 Department of Nuclear Medicine, Faculty of Medicine, Mersin University , Mersin, Turkey
Article information
  • International Journal of Endocrinology and Metabolism: January 01, 2014, 12 (1); e9329
  • Published Online: January 1, 2014
  • Article Type: Case Report
  • Received: December 12, 2012
  • Revised: March 2, 2013
  • Accepted: July 9, 2013
  • DOI: 10.5812/ijem.9329

To Cite: Kara P O, Gunay E C, Erdogan A. Radioiodine Contamination Artifacts and Unusual Patterns of Accumulation in Whole-body I-131 Imaging: A Case Series, Int J Endocrinol Metab. 2014 ; 12(1):e9329. doi: 10.5812/ijem.9329.

Copyright © 2014, Research Institute For Endocrine Sciences and Iran Endocrine Society. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Introduction
2. Cases Presentation
3. Conclusions
  • 1. Lind P, Kohlfurst S. Respective roles of thyroglobulin, radioiodine imaging, and positron emission tomography in the assessment of thyroid cancer. Semin Nucl Med. 2006; 36(3): 194-205[DOI][PubMed]
  • 2. Carlisle MR, Lu C, McDougall IR. The interpretation of 131I scans in the evaluation of thyroid cancer, with an emphasis on false positive findings. Nucl Med Commun. 2003; 24(6): 715-35[DOI][PubMed]
  • 3. Taurog Alvin. Hormone synthesis: thyroid iodine metabolism. 2000;
  • 4. Brown-Grant K. Extrathyroidal iodide concentrating mechanisms. Physiological Rev. 1961; 41(1): 189-213
  • 5. Ozguven M, Ilgan S, Arslan N, Karacalioglu AO, Yuksel D, Dundar S. Unusual patterns of I-131 contamination. Ann Nucl Med. 2004; 18(3): 271-4[PubMed]
  • 6. Pochis WT, Krasnow AZ, Isitman AT, Cerletty JM, Kir KM, Hellman RS, et al. The radioactive handkerchief sign. A contamination artifact in I-131 imaging for metastatic thyroid carcinoma. Clin Nucl Med. 1990; 15(7): 491-4[PubMed]
  • 7. Zettinig G, Karanikas G, Hanselmayer G, Havlik E, Dudczak R. Radioactive contamination of contact lenses during radioiodine therapy. Nucl Med Commun. 2000; 21(10): 955-7[PubMed]
  • 8. Ozguven M, Ilgan S, Karacalioglu AO, Arslan N, Ozturk E. Unusual patterns of I-131 accumulation. Clin Nucl Med. 2004; 29(11): 738-40[PubMed]
  • 9. Ceylan Gunay E, Erdogan A. Mediastinal radioiodine uptake due to hiatal hernia: a false-positive reason in 131I scan. Rev Esp Med Nucl. 2010; 29(2): 95[DOI][PubMed]
  • 10. Bakheet Siema M, Hammami Muhammad M. False-Positive Radioiodine Whole-Body Scan in Thyroid Cancer Patients Due to Unrelated Pathology. Clin Nucl Med. 1994; 19(4): 325-329[DOI]
  • 11. Kiratli PO, Kara PP, Ergun EL, Gedikoglu G. Metastatic insular thyroid carcinoma: visualized on Tc-99m pertechnetate, Tc-99m MDP and iodine-131 scintigraphy; a review of the literature for other radionuclide agents. Ann Nucl Med. 2004; 18(5): 443-6[PubMed]
  • 12. Kara Gedik G, Sarı O, Şahin Ö, Özcan Kara P. Widespread contamination mimicking distant metastases in whole body imaging after I-131 ablative therapy. Turk J Nucl Med. 2009; 18(2): 50-2
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