International Journal of Endocrinology and Metabolism

Published by: Kowsar

Alteration of Lipid Parameters in Patients With Subclinical Hypothyroidism

Bashir Ahmad Laway 1 , * , Fayaz Ahmad War 2 , Sonaullah Shah 2 , Raiz Ahmad Misgar 1 and Suman Kumar Kotwal 1
Authors Information
1 Department of Endocrinology, Sher-I-Kashmir Institute of Medical Sciences, Soura, Srinagar, Kashmir, India
2 Department of Internal Medicine, Sher-I-Kashmir Institute of Medical Sciences, Soura, Srinagar, Kashmir, India
Article information
  • International Journal of Endocrinology and Metabolism: July 01, 2014, 12 (3); e17496
  • Published Online: July 1, 2014
  • Article Type: Research Article
  • Received: January 11, 2014
  • Revised: March 16, 2014
  • Accepted: April 26, 2014
  • DOI: 10.5812/ijem.17496

To Cite: Laway B A, War F A, Shah S, Misgar R A, Kumar Kotwal S. et al. Alteration of Lipid Parameters in Patients With Subclinical Hypothyroidism, Int J Endocrinol Metab. 2014 ;12(3):e17496. doi: 10.5812/ijem.17496.

Abstract
Copyright © 2014, Research Institute For Endocrine Sciences and Iran Endocrine Society. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. Canaris GJ, Manowitz NR, Mayor G, Ridgway EC. The Colorado Thyroid Disease Prevalence Study. JAMA. 2000; 160(4): 526[DOI]
  • 2. Cappola AR, Ladenson PW. Hypothyroidism and atherosclerosis. J Clin Endocrinol Metab. 2003; 88(6): 2438-44[DOI][PubMed]
  • 3. Pucci E, Chiovato L, Pinchera A. Thyroid and lipid metabolism. INT J OBESITY . 2000; 24-12[DOI]
  • 4. Pearce EN. Update in lipid alterations in subclinical hypothyroidism. J Clin Endocrinol Metab. 2012; 97(2): 326-33[DOI][PubMed]
  • 5. Jung CH, Sung KC, Shin HS, Rhee EJ, Lee WY, Kim BS, et al. Thyroid dysfunction and their relation to cardiovascular risk factors such as lipid profile, hsCRP, and waist hip ratio in Korea. Korean J Intern Med. 2003; 18(3): 146-53[PubMed]
  • 6. Walsh JP, Bremner AP, Bulsara MK, O'Leary P, Leedman PJ, Feddema P, et al. Thyroid dysfunction and serum lipids: a community-based study. Clin Endocrinol (Oxf). 2005; 63(6): 670-5[DOI][PubMed]
  • 7. Iqbal A, Jorde R, Figenschau Y. Serum lipid levels in relation to serum thyroid-stimulating hormone and the effect of thyroxine treatment on serum lipid levels in subjects with subclinical hypothyroidism: the Tromso Study. J Intern Med. 2006; 260(1): 53-61[DOI][PubMed]
  • 8. Cooper DS. Subclinical thyroid disease: a clinician's perspective. Ann Intern Med. 1998; 129(2): 135-8[PubMed]
  • 9. Kahaly GJ. Cardiovascular and atherogenic aspects of subclinical hypothyroidism. Thyroid. 2000; 10(8): 665-79[DOI][PubMed]
  • 10. Sahu S, Chawla R, Uppal B. Comparison of two methods of estimation of low density lipoprotein cholesterol, the direct versus friedewald estimation. Indian J Clin Biochem. 2005; 20(2): 54-61[DOI][PubMed]
  • 11. Kricka LJ. Chemiluminescence. Molecular cloning: A laboratory manual. 2001; 3
  • 12. Chait A, Bierman EL, Albers JJ. Regulatory role of triiodothyronine in the degradation of low density lipoprotein by cultured human skin fibroblasts. J Clin Endocrinol Metab. 1979; 48(5): 887-9[DOI][PubMed]
  • 13. Paoli-Valeri M, Guzmán M, Jiménez-López V, Arias-Ferreira A, Briceño-Fernández M, Arata-Bellabarba G. Perfil lipídico aterogénico en niños con hipotiroidismo subclínico. AP. 2005; 62(2): 128-34[DOI]
  • 14. Duntas LH, Wartofsky L. Cardiovascular risk and subclinical hypothyroidism: focus on lipids and new emerging risk factors. What is the evidence? Thyroid. 2007; 17(11): 1075-84[DOI][PubMed]
  • 15. Hueston WJ, Pearson WS. Subclinical hypothyroidism and the risk of hypercholesterolemia. Ann Fam Med. 2004; 2(4): 351-5[PubMed]
  • 16. Vierhapper H, Nardi A, Grosser P, Raber W, Gessl A. Low-density lipoprotein cholesterol in subclinical hypothyroidism. Thyroid. 2000; 10(11): 981-4[PubMed]
  • 17. Kanaya AM, Harris F, Volpato S, Perez-Stable EJ, Harris T, Bauer DC. Association between thyroid dysfunction and total cholesterol level in an older biracial population: the health, aging and body composition study. Arch Intern Med. 2002; 162(7): 773-9[PubMed]
  • 18. Lai Y, Wang J, Jiang F, Wang B, Chen Y, Li M, et al. The relationship between serum thyrotropin and components of metabolic syndrome. Endocr J. 2011; 58(1): 23-30[PubMed]
  • 19. Muller B, Zulewski H, Huber P, Ratcliffe JG, Staub JJ. Impaired action of thyroid hormone associated with smoking in women with hypothyroidism. N Engl J Med. 1995; 333(15): 964-9[DOI][PubMed]
  • 20. Kuusi T, Taskinen MR, Nikkila EA. Lipoproteins, lipolytic enzymes, and hormonal status in hypothyroid women at different levels of substitution. J Clin Endocrinol Metab. 1988; 66(1): 51-6[DOI][PubMed]
  • 21. O'Brien T, Dinneen SF, O'Brien PC, Palumbo PJ. Hyperlipidemia in Patients With Primary and Secondary Hypothyroidism. Mayo Clin Proc. 1993; 68(9): 860-6[DOI]
  • 22. Ganie MA, Laway BA, Wani TA, Zargar MA, Nisar S, Ahamed F, et al. Association of subclinical hypothyroidism and phenotype, insulin resistance, and lipid parameters in young women with polycystic ovary syndrome. Fertil Steril. 2011; 95(6): 2039-43[DOI][PubMed]
  • 23. Borba EF, Carvalho JF, Bonfa E. Mechanisms of dyslipoproteinemias in systemic lupus erythematosus. Clin Dev Immunol. 2006; 13(2-4): 203-8[DOI][PubMed]
  • 24. Efstathiadou Z, Bitsis S, Milionis HJ, Kukuvitis A, Bairaktari ET, Elisaf MS, et al. Lipid profile in subclinical hypothyroidism: is L-thyroxine substitution beneficial? Eur J Endocrinol. 2001; 145(6): 705-10[PubMed]
  • 25. Michalopoulou G, Alevizaki M, Piperingos G, Mitsibounas D, Mantzos E, Adamopoulos P, et al. High serum cholesterol levels in persons with 'high-normal' TSH levels: should one extend the definition of subclinical hypothyroidism? Eur J Endocrinol. 1998; 138(2): 141-5[PubMed]
  • 26. Chubb SA, Davis WA, Davis TM. Interactions among thyroid function, insulin sensitivity, and serum lipid concentrations: the Fremantle diabetes study. J Clin Endocrinol Metab. 2005; 90(9): 5317-20[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:

Author(s):

Article(s):

Create Citiation Alert
via Google Reader

Readers' Comments