International Journal of Endocrinology and Metabolism

Published by: Kowsar

Anti-Thyroid Drugs-Related Myopathy: Is Carbimazole the Real Culprit?

Chiu Chi Tsang 1 , * , Wai Shan Hui 1 , Kwun Man Lo 1 , Jonas Hon Ming Yeung 1 and Yuk Lun Cheng 1
Authors Information
1 Department of Medicine, Alice Ho Miu Ling Nethersole Hospital, Hong Kong, China
Article information
  • International Journal of Endocrinology and Metabolism: January 01, 2015, 13 (1); e17570
  • Published Online: January 22, 2015
  • Article Type: Case Report
  • Received: January 15, 2014
  • Revised: May 16, 2014
  • Accepted: July 15, 2014
  • DOI: 10.5812/ijem.17570

To Cite: Tsang C C, Hui W S, Lo K M, Yeung J H M, Cheng Y L. et al. Anti-Thyroid Drugs-Related Myopathy: Is Carbimazole the Real Culprit?, Int J Endocrinol Metab. 2015 ;13(1):e17570. doi: 10.5812/ijem.17570.

Abstract
Copyright: Copyright © 0, International Journal of Endocrinology and Metabolism. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Introduction
2. Case Presentation
3. Discussion
Footnote
References
  • 1. Waltuck J. Musculoskeletal manifestations of thyroid disease. Bull Rheum Dis. 2000; 49(11): 1-3[PubMed]
  • 2. Cooper DS. Antithyroid drugs for the treatment of hyperthyroidism caused by Graves' disease. Endocrinol Metab Clin North Am. 1998; 27(1): 225-47[PubMed]
  • 3. Pasquier E, Genereau T, Baudrimont M, Cabane J, Biour M, Imbert JC. Biopsy-proven myositis with microvasculitis in association with carbimazole. Lancet. 1991; 338(8774): 1082-3[PubMed]
  • 4. Mizuno H, Sugiyama Y, Nishi Y, Ueda N, Ohro Y, Togari H. Elevation of serum creatine kinase in response to medical treatment of Graves' disease in children. Acta Paediatr. 2006; 95(2): 243-5[DOI][PubMed]
  • 5. Lim AY, Kek PC, Soh AW. Carbimazole-induced myositis in the treatment of Graves' disease: a complication in genetically susceptible individuals? Singapore Med J. 2013; 54(7)-6[PubMed]
  • 6. Suzuki S, Ichikawa K, Nagai M, Mikoshiba M, Mori J, Kaneko A, et al. Elevation of serum creatine kinase during treatment with antithyroid drugs in patients with hyperthyroidism due to Graves disease. A novel side effect of antithyroid drugs. Arch Intern Med. 1997; 157(6): 693-6[PubMed]
  • 7. Kung AW, Ma JT, Yu YL, Wang CC, Woo EK, Lam KS, et al. Myopathy in acute hypothyroidism. Postgrad Med J. 1987; 63(742): 661-3[PubMed]
  • 8. Shaheen D, Kim CS. Myositis associated with the decline of thyroid hormone levels in thyrotoxicosis: a syndrome? Thyroid. 2009; 19(12): 1413-7[DOI][PubMed]
  • 9. Page SR, Nussey SS. Myositis in association with carbimazole therapy. Lancet. 1989; 1(8644): 964[PubMed]
  • 10. Shergy WJ, Caldwell DS. Polymyositis after propylthiouracil treatment for hyperthyroidism. Ann Rheum Dis. 1988; 47(4): 340-3[PubMed]
  • 11. Hardiman O, Molloy F, Brett F, Farrell M. Inflammatory myopathy in thyrotoxicosis. Neurology. 1997; 48(2): 339-41[PubMed]
  • 12. Anwar S, Gibofsky A. Musculoskeletal manifestations of thyroid disease. Rheum Dis Clin North Am. 2010; 36(4): 637-46[DOI][PubMed]
  • 13. Fessel WJ. Myopathy of hypothyroidism. Ann Rheum Dis. 1968; 27(6): 590-6[PubMed]
  • 14. Duyff RF, Van den Bosch J, Laman DM, van Loon BJ, Linssen WH. Neuromuscular findings in thyroid dysfunction: a prospective clinical and electrodiagnostic study. J Neurol Neurosurg Psychiatry. 2000; 68(6): 750-5[PubMed]
  • 15. Goswami R, Shah P, Ammini AC. Thyrotoxicosis with osteomalacia and proximal myopathy. J Postgrad Med. 1993; 39(2): 89-90[PubMed]
  • 16. Alvarez F, Pagot C, Vabre-Latre CM, Uro-Coste E, Paul C, Chaix Y, et al. Carbimazole-induced juvenile dermatomyositis. Br J Dermatol. 2008; 158(1): 196-7[DOI][PubMed]
  • 17. Benavides VC, Rivkees SA. Myopathy Associated with Acute Hypothyroidism following Radioiodine Therapy for Graves Disease in an Adolescent. Int J Pediatr Endocrinol. 2010; 2010(1): 717303[DOI][PubMed]
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