Hypothyroidism and Lipid Levels in a Community Based Study (TTS)

Authors Information
Article Notes and Dates
To Cite : Alamdari S, Amouzegar A, Tohidi M, Gharibzadeh S, Kheirkhah P, et al. Hypothyroidism and Lipid Levels in a Community Based Study (TTS), Int J Endocrinol Metab. 2016 ;14(1):e22827. doi: 10.5812/ijem.22827.
Copyright: Copyright © 2016, International Journal of Endocrinology and Metabolism. .
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
  • 1. Velkoska Nakova V, Krstevska B, Bosevski M, Dimitrovski C, Serafimoski V. Dyslipidaemia and hypertension in patients with subclinical hypothyroidism. Prilozi. 2009; 30(2): 93-102[PubMed]
  • 2. Pearce EN. Hypothyroidism and dyslipidemia: modern concepts and approaches. Curr Cardiol Rep. 2004; 6(6): 451-6[PubMed]
  • 3. Rizos CV, Elisaf MS, Liberopoulos EN. Effects of thyroid dysfunction on lipid profile. Open Cardiovasc Med J. 2011; 5: 76-84[DOI][PubMed]
  • 4. Efstathiadou Z, Bitsis S, Milionis HJ, Kukuvitis A, Bairaktari ET, Elisaf MS, et al. Lipid profile in subclinical hypothyroidism: is L-thyroxine substitution beneficial? Eur J Endocrinol. 2001; 145(6): 705-10[PubMed]
  • 5. Bell RJ, Rivera-Woll L, Davison SL, Topliss DJ, Donath S, Davis SR. Well-being, health-related quality of life and cardiovascular disease risk profile in women with subclinical thyroid disease - a community-based study. Clin Endocrinol. 2007; 66(4): 548-56
  • 6. Hueston WJ, Pearson WS. Subclinical hypothyroidism and the risk of hypercholesterolemia. Ann Fam Med. 2004; 2(4): 351-5[PubMed]
  • 7. Hak AE, Pols HA, Visser TJ, Drexhage HA, Hofman A, Witteman JC. Subclinical hypothyroidism is an independent risk factor for atherosclerosis and myocardial infarction in elderly women: the Rotterdam Study. Ann Intern Med. 2000; 132(4): 270-8[PubMed]
  • 8. Neves C, Alves M, Medina JL, Delgado JL. Thyroid diseases, dyslipidemia and cardiovascular pathology. Rev Port Cardiol. 2008; 27(10): 1211-36[PubMed]
  • 9. Kalantari S, Naghipour M. Statin therapy and hepatotoxicity: Appraisal of the safety profile of atorvastatin in hyperlipidemic patients. Adv Biomed Res. 2014; 3: 168[DOI][PubMed]
  • 10. Canaris GJ, Manowitz NR, Mayor G, Ridgway EC. The Colorado thyroid disease prevalence study. Arch Intern Med. 2000; 160(4): 526-34[PubMed]
  • 11. Jung CH, Sung KC, Shin HS, Rhee EJ, Lee WY, Kim BS, et al. Thyroid dysfunction and their relation to cardiovascular risk factors such as lipid profile, hsCRP, and waist hip ratio in Korea. Korean J Intern Med. 2003; 18(3): 146-53[PubMed]
  • 12. Kalantari S, Heidarzadeh A. Thyroxine Therapy Improves Serum Lipoproteins and Some Clinical Findings In Patients With Subclinical Hypothyroidism. Int J Endocrinol Metabol. 2006; 4(2): 106-11
  • 13. Mansourian AR. The state of serum lipids profiles in sub-clinical hypothyroidism: a review of the literature. Pak J Biol Sci. 2010; 13(11): 556-62[PubMed]
  • 14. Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 1972; 18(6): 499-502[PubMed]
  • 15. Amouzegar A, Delshad H, Mehran L, Tohidi M, Khafaji F, Azizi F. Reference limit of thyrotropin (TSH) and free thyroxine (FT4) in thyroperoxidase positive and negative subjects: a population based study. J Endocrinol Invest. 2013; 36(11): 950-4[DOI][PubMed]
  • 16. Walsh JP, Bremner AP, Bulsara MK, O'Leary P, Leedman PJ, Feddema P, et al. Thyroid dysfunction and serum lipids: a community-based study. Clin Endocrinol (Oxf). 2005; 63(6): 670-5[DOI][PubMed]
  • 17. Boekholdt SM, Titan SM, Wiersinga WM, Chatterjee K, Basart DC, Luben R, et al. Initial thyroid status and cardiovascular risk factors: the EPIC-Norfolk prospective population study. Clin Endocrinol (Oxf). 2010; 72(3): 404-10[DOI][PubMed]
  • 18. Pirich C, Mullner M, Sinzinger H. Prevalence and relevance of thyroid dysfunction in 1922 cholesterol screening participants. J Clin Epidemiol. 2000; 53(6): 623-9[PubMed]
  • 19. Kim BJ, Kim TY, Koh JM, Kim HK, Park JY, Lee KU, et al. Relationship between serum free T4 (FT4) levels and metabolic syndrome (MS) and its components in healthy euthyroid subjects. Clin Endocrinol (Oxf). 2009; 70(1): 152-60[DOI][PubMed]
  • 20. Chin KY, Ima-Nirwana S, Mohamed IN, Aminuddin A, Johari MH, Ngah WZ. The relationships between thyroid hormones and thyroid-stimulating hormone with lipid profile in euthyroid men. Int J Med Sci. 2014; 11(4): 349-55[DOI][PubMed]
  • 21. Roos A, Bakker SJ, Links TP, Gans RO, Wolffenbuttel BH. Thyroid function is associated with components of the metabolic syndrome in euthyroid subjects. J Clin Endocrinol Metab. 2007; 92(2): 491-6[DOI][PubMed]
  • 22. Garduno-Garcia Jde J, Alvirde-Garcia U, Lopez-Carrasco G, Padilla Mendoza ME, Mehta R, Arellano-Campos O, et al. TSH and free thyroxine concentrations are associated with differing metabolic markers in euthyroid subjects. Eur J Endocrinol. 2010; 163(2): 273-8[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiaion Alert via Google Reader

Cited By:

International Journal of Endocrinology and Metabolism accepts terms & conditions of:

International Committee of Medical Journal Editors (ICMJE) Citedby Linking DOI enabled Crossref iThenticate COPE Cross Check