International Journal of Endocrinology and Metabolism

Published by: Kowsar

Primordial and Primary Preventions of Thyroid Disease

Fereidoun Azizi 1 , Ladan Mehran 1 , Farhad Hosseinpanah 2 , Hossein Delshad 2 and Atieh Amouzegar 1 , *
Authors Information
1 Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran
2 Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran
Article information
  • International Journal of Endocrinology and Metabolism: October 2017, 15 (4); e57871
  • Published Online: October 7, 2017
  • Article Type: Review Article
  • Received: April 5, 2017
  • Revised: July 9, 2017
  • Accepted: August 14, 2017
  • DOI: 10.5812/ijem.57871

To Cite: Azizi F, Mehran L, Hosseinpanah F, Delshad H, Amouzegar A. et al. Primordial and Primary Preventions of Thyroid Disease, Int J Endocrinol Metab. 2017 ;15(4):e57871. doi: 10.5812/ijem.57871.

Abstract
Copyright: Copyright © 2017, International Journal of Endocrinology and Metabolism. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Introduction
2. Methods
3. Closing Remarks and Direction of Future Research
Acknowledgements
Footnotes
References
  • 1. M N. Health protection from vision of traditional iranian medicine (in Persian). 2012;
  • 2. Bonita R, Beaglehole R, Kjellstrom T. Basic epidemiology. 2006;
  • 3. Starfield B. Basic concepts in population health and health care. J Epidemiol Community Health. 2001; 55(7): 452-4[PubMed]
  • 4. Murray CJ, Anderson B, Burstein R, Leach-Kemon K, Schneider M, Tardif A, et al. Development assistance for health: trends and prospects. Lancet. 2011; 378(9785): 8-10[DOI][PubMed]
  • 5. Hetzel B. The nature and magnitude of the iodine deficiency disorders. Towards the global elimination of brain damage due to iodine deficiency . 2004;
  • 6. Cooper DS, Ridgway EC. Thoughts on prevention of thyroid disease in the United States. Thyroid. 2002; 12(10): 925-9[DOI][PubMed]
  • 7. Zimmermann MB, Jooste PL, Pandav CS. Iodine-deficiency disorders. Lancet. 2008; 372(9645): 1251-62[DOI][PubMed]
  • 8. de Benoist B, McLean E, Andersson M, Rogers L. Iodine deficiency in 2007: global progress since 2003. Food Nutr Bull. 2008; 29(3): 195-202[DOI][PubMed]
  • 9. W. H. O. Secretariat , Andersson M, de Benoist B, Delange F, Zupan J. Prevention and control of iodine deficiency in pregnant and lactating women and in children less than 2-years-old: conclusions and recommendations of the Technical Consultation. Public Health Nutr. 2007; 10(12A): 1606-11[DOI][PubMed]
  • 10. Azizi F. Iodized oil: its role in the management of iodine deficiency disorders. Int J Endocrinol Metab. 2007; 2007(2): 91-8
  • 11. Assessment of iodine deficiency disorders and monitoring their elimination: a guide for programme managers. 2007;
  • 12. The WHO vitamin and mineral nutrition information system (VMNIS) on iodine deficiency disorders. 2009;
  • 13. ICCIDD global network. . Website of the international council for the control of iodine deficiency disorders. .
  • 14. Zimmermann MB. Symposium on 'Geographical and geological influences on nutrition': Iodine deficiency in industrialised countries. Proc Nutr Soc. 2010; 69(1): 133-43[DOI][PubMed]
  • 15. Caldwell KL, Pan Y, Mortensen ME, Makhmudov A, Merrill L, Moye J. Iodine status in pregnant women in the National Children's Study and in U.S. women (15-44 years), National Health and Nutrition Examination Survey 2005-2010. Thyroid. 2013; 23(8): 927-37[DOI][PubMed]
  • 16. Sustaining the elimination of iodine deficiency disorders. 2005;
  • 17. Delshad H, Amouzegar A, Mirmiran P, Mehran L, Azizi F. Eighteen years of continuously sustained elimination of iodine deficiency in the Islamic Republic of Iran: the vitality of periodic monitoring. Thyroid. 2012; 22(4): 415-21[DOI][PubMed]
  • 18. Azizi F, Mehran L, Sheikholeslam R, Ordookhani A, Naghavi M, Hedayati M, et al. Sustainability of a well-monitored salt iodization program in Iran: marked reduction in goiter prevalence and eventual normalization of urinary iodine concentrations without alteration in iodine content of salt. J Endocrinol Invest. 2008; 31(5): 422-31[DOI][PubMed]
  • 19. Elimination of iodine deficiency disorders: a manual for health workers. 2008;
  • 20. Bergman A, Heindel JJ, Jobling S, Kidd K, Zoeller TR. State of the science of endocrine disrupting chemicals 2012: summary for decision-makers. 2013;
  • 21. Braverman LE, Cooper DS. Werner & Ingbar's the thyroid: a fundamental and clinical text. 2012;
  • 22. Boas M, Feldt-Rasmussen U, Main KM. Thyroid effects of endocrine disrupting chemicals. Mol Cell Endocrinol. 2012; 355(2): 240-8[DOI][PubMed]
  • 23. Romano ME, Webster GM, Vuong AM, Thomas Zoeller R, Chen A, Hoofnagle AN, et al. Gestational urinary bisphenol A and maternal and newborn thyroid hormone concentrations: the HOME Study. Environ Res. 2015; 138: 453-60[DOI][PubMed]
  • 24. Wang T, Lu J, Xu M, Xu Y, Li M, Liu Y, et al. Urinary bisphenol a concentration and thyroid function in Chinese adults. Epidemiology. 2013; 24(2): 295-302[DOI][PubMed]
  • 25. Braverman LE, He X, Pino S, Cross M, Magnani B, Lamm SH, et al. The effect of perchlorate, thiocyanate, and nitrate on thyroid function in workers exposed to perchlorate long-term. J Clin Endocrinol Metab. 2005; 90(2): 700-6[DOI][PubMed]
  • 26. Messina M, Redmond G. Effects of soy protein and soybean isoflavones on thyroid function in healthy adults and hypothyroid patients: a review of the relevant literature. Thyroid. 2006; 16(3): 249-58[DOI][PubMed]
  • 27. Giuliani C, Bucci I, Di Santo S, Rossi C, Grassadonia A, Piantelli M, et al. The flavonoid quercetin inhibits thyroid-restricted genes expression and thyroid function. Food Chem Toxicol. 2014; 66: 23-9[DOI][PubMed]
  • 28. Daniel AT, Adekilekun TA, Adewale MA, Adekemi AT. Cyanide-induced hyperthyroidism in male Wistar rats. Niger Med J. 2014; 55(3): 246-9[DOI][PubMed]
  • 29. Giuliani C, Bucci I, Di Santo S, Rossi C, Grassadonia A, Mariotti M, et al. Resveratrol inhibits sodium/iodide symporter gene expression and function in rat thyroid cells. PLoS One. 2014; 9(9): 107936[DOI][PubMed]
  • 30. Iaglova NV, Iaglov VV. [Alteration of thyroid hormone secretion after long-term exposure to low doses of endocrine disruptor DDT]. Biomed Khim. 2014; 60(6): 655-60[PubMed]
  • 31. Yaglova NV, Yaglov VV. Changes in thyroid status of rats after prolonged exposure to low dose dichlorodiphenyltrichloroethane. Bull Exp Biol Med. 2014; 156(6): 760-2[DOI][PubMed]
  • 32. Martuzzi M, Tickner JA. The precautionary principle: protecting public health, the environment and the future of our children. 2004;
  • 33. Hutfless S, Matos P, Talor MV, Caturegli P, Rose NR. Significance of prediagnostic thyroid antibodies in women with autoimmune thyroid disease. J Clin Endocrinol Metab. 2011; 96(9)-71[DOI][PubMed]
  • 34. Nielsen CH, Leslie RG, Jepsen BS, Kazatchkine MD, Kaveri SV, Fischer E. Natural autoantibodies and complement promote the uptake of a self antigen, human thyroglobulin, by B cells and the proliferation of thyroglobulin-reactive CD4(+) T cells in healthy individuals. Eur J Immunol. 2001; 31(9): 2660-8[PubMed]
  • 35. Lidman K, Eriksson U, Norberg R, Fagraeus A. Indirect immunofluorescence staining of human thyroid by antibodies occurring in Yersinia enterocolitica infections. Clin Exp Immunol. 1976; 23(3): 429-35[PubMed]
  • 36. Weetman A, DeGroot LJ. Autoimmunity to the thyroid gland. Endocrinology of Pregnancy. 2000;
  • 37. Irvine WJ, Davies SH, Teitelbaum S, Delamore IW, Williams AW. The clinical and pathological significance of gastric parietal cell antibody. Ann N Y Acad Sci. 1965; 124(2): 657-91[PubMed]
  • 38. Doniach D, Ro Itt IM, Taylor KB. Autoimmune phenomena in pernicious anaemia. Serological overlap with thyroiditis, thyrotoxicosis, and systemic lupus erythematosus. Br Med J. 1963; 1(5342): 1374-9[PubMed]
  • 39. Tudhope GR, Wilson GM. Deficiency of vitamin B12 in hypothyroidism. Lancet. 1962; 1(7232): 703-6[PubMed]
  • 40. Naiyer AJ, Shah J, Hernandez L, Kim SY, Ciaccio EJ, Cheng J, et al. Tissue transglutaminase antibodies in individuals with celiac disease bind to thyroid follicles and extracellular matrix and may contribute to thyroid dysfunction. Thyroid. 2008; 18(11): 1171-8[DOI][PubMed]
  • 41. Buchanan WW, Crooks J, Alexander WD, Koutras DA, Wayne EJ, Gray KG. Association of Hashimoto's thyroiditis and rheumatoid arthritis. Lancet. 1961; 277(7171): 245-8
  • 42. Mulhern LM, Masi AT, Shulman LE. Hashimoto's disease. A search for associated disorders in 170 clinically detected cases. Lancet. 1966; 2(7462): 508-11[PubMed]
  • 43. Morita S, Arima T, Matsuda M. Prevalence of nonthyroid specific autoantibodies in autoimmune thyroid diseases. J Clin Endocrinol Metab. 1995; 80(4): 1203-6[DOI][PubMed]
  • 44. Dobson R, Giovannoni G. Autoimmune disease in people with multiple sclerosis and their relatives: a systematic review and meta-analysis. J Neurol. 2013; 260(5): 1272-85[DOI][PubMed]
  • 45. Neufeld M, Maclaren NK, Blizzard RM. Two types of autoimmune Addison's disease associated with different polyglandular autoimmune (PGA) syndromes. Medicine (Baltimore). 1981; 60(5): 355-62[PubMed]
  • 46. Falorni A, Laureti S, Santeusanio F. Autoantibodies in autoimmune polyendocrine syndrome type II. Endocrinol Metab Clin North Am. 2002; 31(2): 369-89[PubMed]
  • 47. Weetman AP. Autoimmunity to steroid-producing cells and familial polyendocrine autoimmunity. Baillieres Clin Endocrinol Metab. 1995; 9(1): 157-74[PubMed]
  • 48. Ahonen P, Myllarniemi S, Sipila I, Perheentupa J. Clinical variation of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) in a series of 68 patients. N Engl J Med. 1990; 322(26): 1829-36[DOI][PubMed]
  • 49. Nithiyananthan R, Heward JM, Allahabadia A, Barnett AH, Franklyn JA, Gough SC. A heterozygous deletion of the autoimmune regulator (AIRE1) gene, autoimmune thyroid disease, and type 1 diabetes: no evidence for association. J Clin Endocrinol Metab. 2000; 85(3): 1320-2[DOI][PubMed]
  • 50. Benvenga S, Trimarchi F. Changed presentation of Hashimoto's thyroiditis in North-Eastern Sicily and Calabria (Southern Italy) based on a 31-year experience. Thyroid. 2008; 18(4): 429-41[DOI][PubMed]
  • 51. Caturegli P, De Remigis A, Chuang K, Dembele M, Iwama A, Iwama S. Hashimoto's thyroiditis: celebrating the centennial through the lens of the Johns Hopkins hospital surgical pathology records. Thyroid. 2013; 23(2): 142-50[DOI][PubMed]
  • 52. Ott J, Meusel M, Schultheis A, Promberger R, Pallikunnel SJ, Neuhold N, et al. The incidence of lymphocytic thyroid infiltration and Hashimoto's thyroiditis increased in patients operated for benign goiter over a 31-year period. Virchows Arch. 2011; 459(3): 277-81[DOI][PubMed]
  • 53. Wong GW, Cheng PS. Increasing incidence of childhood Graves' disease in Hong Kong: a follow-up study. Clin Endocrinol (Oxf). 2001; 54(4): 547-50[PubMed]
  • 54. Kondrashova A, Viskari H, Haapala AM, Seiskari T, Kulmala P, Ilonen J, et al. Serological evidence of thyroid autoimmunity among schoolchildren in two different socioeconomic environments. J Clin Endocrinol Metab. 2008; 93(3): 729-34[DOI][PubMed]
  • 55. Atkins MB, Mier JW, Parkinson DR, Gould JA, Berkman EM, Kaplan MM. Hypothyroidism after treatment with interleukin-2 and lymphokine-activated killer cells. N Engl J Med. 1988; 318(24): 1557-63[DOI][PubMed]
  • 56. Gilquin J, Viard JP, Jubault V, Sert C, Kazatchkine MD. Delayed occurrence of Graves' disease after immune restoration with HAART. Highly active antiretroviral therapy. Lancet. 1998; 352(9144): 1907-8[PubMed]
  • 57. Durelli L, Ferrero B, Oggero A, Verdun E, Ghezzi A, Montanari E, et al. Thyroid function and autoimmunity during interferon beta-1b treatment: a multicenter prospective study. J Clin Endocrinol Metab. 2001; 86(8): 3525-32[DOI][PubMed]
  • 58. Caraccio N, Dardano A, Manfredonia F, Manca L, Pasquali L, Iudice A, et al. Long-term follow-up of 106 multiple sclerosis patients undergoing interferon-beta 1a or 1b therapy: predictive factors of thyroid disease development and duration. J Clin Endocrinol Metab. 2005; 90(7): 4133-7[DOI][PubMed]
  • 59. Hidaka Y, Amino N, Iwatani Y, Itoh E, Matsunaga M, Tamaki H. Recurrence of thyrotoxicosis after attack of allergic rhinitis in patients with Graves' disease. J Clin Endocrinol Metab. 1993; 77(6): 1667-70[DOI][PubMed]
  • 60. Yamada T, Sato A, Komiya I, Nishimori T, Ito Y, Terao A, et al. An elevation of serum immunoglobulin E provides a new aspect of hyperthyroid Graves' disease. J Clin Endocrinol Metab. 2000; 85(8): 2775-8[DOI][PubMed]
  • 61. Bartalena L, Bogazzi F, Tanda ML, Manetti L, Dell'Unto E, Martino E. Cigarette smoking and the thyroid. Eur J Endocrinol. 1995; 133(5): 507-12[PubMed]
  • 62. Andersen SL, Olsen J, Wu CS, Laurberg P. Smoking reduces the risk of hypothyroidism and increases the risk of hyperthyroidism: evidence from 450,842 mothers giving birth in Denmark. Clin Endocrinol (Oxf). 2014; 80(2): 307-14[DOI][PubMed]
  • 63. Rumold R, Jyrala M, Diaz-Sanchez D. Secondhand smoke induces allergic sensitization in mice. J Immunol. 2001; 167(8): 4765-70[PubMed]
  • 64. Belin RM, Astor BC, Powe NR, Ladenson PW. Smoke exposure is associated with a lower prevalence of serum thyroid autoantibodies and thyrotropin concentration elevation and a higher prevalence of mild thyrotropin concentration suppression in the third National Health and Nutrition Examination Survey (NHANES III). J Clin Endocrinol Metab. 2004; 89(12): 6077-86[DOI][PubMed]
  • 65. Carle A, Bulow Pedersen I, Knudsen N, Perrild H, Ovesen L, Banke Rasmussen L, et al. Smoking cessation is followed by a sharp but transient rise in the incidence of overt autoimmune hypothyroidism - a population-based, case-control study. Clin Endocrinol (Oxf). 2012; 77(5): 764-72[DOI][PubMed]
  • 66. Schmeltz LR, Blevins TC, Aronoff SL, Ozer K, Leffert JD, Goldberg MA, et al. Anatabine supplementation decreases thyroglobulin antibodies in patients with chronic lymphocytic autoimmune (Hashimoto's) thyroiditis: a randomized controlled clinical trial. J Clin Endocrinol Metab. 2014; 99(1)-42[DOI][PubMed]
  • 67. Gu JY, Qian CH, Tang W, Wu XH, Xu KF, Scherbaum WA, et al. Polychlorinated biphenyls affect thyroid function and induce autoimmunity in Sprague-Dawley rats. Horm Metab Res. 2009; 41(6): 471-4[PubMed]
  • 68. de Freitas CU, Grimaldi Campos RA, Rodrigues Silva MA, Panachao MR, de Moraes JC, Waissmann W, et al. Can living in the surroundings of a petrochemical complex be a risk factor for autoimmune thyroid disease? Environ Res. 2010; 110(1): 112-7[DOI][PubMed]
  • 69. Goldner WS, Sandler DP, Yu F, Hoppin JA, Kamel F, Levan TD. Pesticide use and thyroid disease among women in the Agricultural Health Study. Am J Epidemiol. 2010; 171(4): 455-64[DOI][PubMed]
  • 70. Papanastasiou L, Alevizaki M, Piperingos G, Mantzos E, Tseleni-Balafouta S, Koutras DA. The effect of iodine administration on the development of thyroid autoimmunity in patients with nontoxic goiter. Thyroid. 2000; 10(6): 493-7[DOI][PubMed]
  • 71. Teng X, Shan Z, Chen Y, Lai Y, Yu J, Shan L, et al. More than adequate iodine intake may increase subclinical hypothyroidism and autoimmune thyroiditis: a cross-sectional study based on two Chinese communities with different iodine intake levels. Eur J Endocrinol. 2011; 164(6): 943-50[DOI][PubMed]
  • 72. Zois C, Stavrou I, Svarna E, Seferiadis K, Tsatsoulis A. Natural course of autoimmune thyroiditis after elimination of iodine deficiency in northwestern Greece. Thyroid. 2006; 16(3): 289-93[DOI][PubMed]
  • 73. Yamazaki K, Tanigawa K, Suzuki K, Yamada E, Yamada T, Takano K, et al. Iodide-induced chemokines and genes related to immunological function in cultured human thyroid follicles in the presence of thyrotropin. Thyroid. 2010; 20(1): 67-76[DOI][PubMed]
  • 74. Turker O, Kumanlioglu K, Karapolat I, Dogan I. Selenium treatment in autoimmune thyroiditis: 9-month follow-up with variable doses. J Endocrinol. 2006; 190(1): 151-6[DOI][PubMed]
  • 75. Goswami R, Marwaha RK, Gupta N, Tandon N, Sreenivas V, Tomar N, et al. Prevalence of vitamin D deficiency and its relationship with thyroid autoimmunity in Asian Indians: a community-based survey. Br J Nutr. 2009; 102(3): 382-6[DOI][PubMed]
  • 76. Frisch M, Nielsen NM, Pedersen BV. Same-sex marriage, autoimmune thyroid gland dysfunction and other autoimmune diseases in Denmark 1989-2008. Eur J Epidemiol. 2014; 29(1): 63-71[DOI][PubMed]
  • 77. Chiovato L, Pinchera A. Stressful life events and Graves' disease. Eur J Endocrinol. 1996; 134(6): 680-2[PubMed]
  • 78. Strieder TG, Prummel MF, Tijssen JG, Brosschot JF, Wiersinga WM. Stress is not associated with thyroid peroxidase autoantibodies in euthyroid women. Brain Behav Immun. 2005; 19(3): 203-6[DOI][PubMed]
  • 79. Saint-Mezard P, Chavagnac C, Bosset S, Ionescu M, Peyron E, Kaiserlian D, et al. Psychological stress exerts an adjuvant effect on skin dendritic cell functions in vivo. J Immunol. 2003; 171(8): 4073-80[PubMed]
  • 80. Steinman L. Elaborate interactions between the immune and nervous systems. Nat Immunol. 2004; 5(6): 575-81[DOI][PubMed]
  • 81. Carle A, Bulow Pedersen I, Knudsen N, Perrild H, Ovesen L, Rasmussen LB, et al. Graves' hyperthyroidism and moderate alcohol consumption: evidence for disease prevention. Clin Endocrinol (Oxf). 2013; 79(1): 111-9[DOI][PubMed]
  • 82. Carle A, Pedersen IB, Knudsen N, Perrild H, Ovesen L, Rasmussen LB, et al. Moderate alcohol consumption may protect against overt autoimmune hypothyroidism: a population-based case-control study. Eur J Endocrinol. 2012; 167(4): 483-90[DOI][PubMed]
  • 83. Effraimidis G, Tijssen JG, Wiersinga WM. Alcohol consumption as a risk factor for autoimmune thyroid disease: a prospective study. Eur Thyroid J. 2012; 1(2): 99-104[DOI][PubMed]
  • 84. Asaria P, Chisholm D, Mathers C, Ezzati M, Beaglehole R. Chronic disease prevention: health effects and financial costs of strategies to reduce salt intake and control tobacco use. Lancet. 2007; 370(9604): 2044-53[DOI][PubMed]
  • 85. Laurberg P, Nohr SB, Pedersen KM, Fuglsang E. Iodine nutrition in breast-fed infants is impaired by maternal smoking. J Clin Endocrinol Metab. 2004; 89(1): 181-7[DOI][PubMed]
  • 86. Knudsen N, Bulow I, Laurberg P, Perrild H, Ovesen L, Jorgensen T. High occurrence of thyroid multinodularity and low occurrence of subclinical hypothyroidism among tobacco smokers in a large population study. J Endocrinol. 2002; 175(3): 571-6[PubMed]
  • 87. Prummel MF, Wiersinga WM. Smoking and risk of Graves' disease. JAMA. 1993; 269(4): 479-82[PubMed]
  • 88. Pedersen IB, Laurberg P, Knudsen N, Jorgensen T, Perrild H, Ovesen L, et al. Smoking is negatively associated with the presence of thyroglobulin autoantibody and to a lesser degree with thyroid peroxidase autoantibody in serum: a population study. Eur J Endocrinol. 2008; 158(3): 367-73[DOI][PubMed]
  • 89. Effraimidis G, Tijssen JG, Wiersinga WM. Discontinuation of smoking increases the risk for developing thyroid peroxidase antibodies and/or thyroglobulin antibodies: a prospective study. J Clin Endocrinol Metab. 2009; 94(4): 1324-8[DOI][PubMed]
  • 90. Kreiger N, Parkes R. Cigarette smoking and the risk of thyroid cancer. Eur J Cancer. 2000; 36(15): 1969-73[PubMed]
  • 91. Holm IA, Manson JE, Michels KB, Alexander EK, Willett WC, Utiger RD. Smoking and other lifestyle factors and the risk of Graves' hyperthyroidism. Arch Intern Med. 2005; 165(14): 1606-11[DOI][PubMed]
  • 92. Winsa B, Adami HO, Bergstrom R, Gamstedt A, Dahlberg PA, Adamson U, et al. Stressful life events and Graves' disease. Lancet. 1991; 338(8781): 1475-9[PubMed]
  • 93. Negro R, Stagnaro-Green A. Thyroid autoantibodies, preterm birth, and miscarriage. BMJ. 2011; 342[DOI][PubMed]
  • 94. Ban Y, Greenberg DA, Davies TF, Jacobson E, Concepcion E, Tomer Y. 'Linkage analysis of thyroid antibody production: evidence for shared susceptibility to clinical autoimmune thyroid disease. J Clin Endocrinol Metab. 2008; 93(9): 3589-96[DOI][PubMed]
  • 95. Menconi F, Monti MC, Greenberg DA, Oashi T, Osman R, Davies TF, et al. Molecular amino acid signatures in the MHC class II peptide-binding pocket predispose to autoimmune thyroiditis in humans and in mice. Proc Natl Acad Sci U S A. 2008; 105(37): 14034-9[DOI][PubMed]
  • 96. Amouzegar A, Gharibzadeh S, Kazemian E, Mehran L, Tohidi M, Azizi F. The Prevalence, Incidence and Natural Course of Positive Antithyroperoxidase Antibodies in a Population-Based Study: Tehran Thyroid Study. PLoS One. 2017; 12(1): 169283[DOI][PubMed]
  • 97. Hollowell JG, Staehling NW, Flanders WD, Hannon WH, Gunter EW, Spencer CA, et al. Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III). J Clin Endocrinol Metab. 2002; 87(2): 489-99[DOI][PubMed]
  • 98. Huber G, Staub JJ, Meier C, Mitrache C, Guglielmetti M, Huber P, et al. Prospective study of the spontaneous course of subclinical hypothyroidism: prognostic value of thyrotropin, thyroid reserve, and thyroid antibodies. J Clin Endocrinol Metab. 2002; 87(7): 3221-6[DOI][PubMed]
  • 99. Kubota S, Fujiwara M, Hagiwara H, Tsujimoto N, Takata K, Kudo T, et al. Multiple thyroid cysts may be a cause of hypothyroidism in patients with relatively high iodine intake. Thyroid. 2010; 20(2): 205-8[DOI][PubMed]
  • 100. Fu J, Jiang Y, Liang L, Zhu H. Risk factors of primary thyroid dysfunction in early infants born to mothers with autoimmune thyroid disease. Acta Paediatr. 2005; 94(8): 1043-8[DOI][PubMed]
  • 101. Laurberg P, Nygaard B, Glinoer D, Grussendorf M, Orgiazzi J. Guidelines for TSH-receptor antibody measurements in pregnancy: results of an evidence-based symposium organized by the European Thyroid Association. Eur J Endocrinol. 1998; 139(6): 584-6[PubMed]
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