International Journal of Endocrinology and Metabolism

Published by: Kowsar

Age and Gender Specific Thyroid Hormones and Their Relationships with Body Mass Index in a Large Chinese Population

Qianqian Song 1 , Xinxin Chen 1 , Yang Su 2 , 3 , Zhen Xie 4 , 2 , Shu Wang 1 and Bin Cui 1 , *
Authors Information
1 Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China
2 Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital, Chengdu, China
3 Clinical Laboratory, Sichuan Academy of Medical Sciences, Sichuan Provincial People’s Hospital, Chengdu, China
4 Department of Dermatology, Sichuan Academy of Medical Sciences, Sichuan Provincial People’s Hospital, Chengdu, China
Article information
  • International Journal of Endocrinology and Metabolism: 17 (1); e66450
  • Published Online: January 23, 2019
  • Article Type: Research Article
  • Received: January 19, 2018
  • Revised: December 26, 2018
  • Accepted: January 12, 2019
  • DOI: 10.5812/ijem.66450

To Cite: Song Q, Chen X, Su Y, Xie Z, Wang S, et al. Age and Gender Specific Thyroid Hormones and Their Relationships with Body Mass Index in a Large Chinese Population, Int J Endocrinol Metab. Online ahead of Print ; 17(1):e66450. doi: 10.5812/ijem.66450.

Abstract
Copyright © 2019, International Journal of Endocrinology and Metabolism. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. De Pergola G, Ciampolillo A, Paolotti S, Trerotoli P, Giorgino R. Free triiodothyronine and thyroid stimulating hormone are directly associated with waist circumference, independently of insulin resistance, metabolic parameters and blood pressure in overweight and obese women. Clin Endocrinol (Oxf). 2007;67(2):265-9. doi: 10.1111/j.1365-2265.2007.02874.x. [PubMed: 17547687].
  • 2. Torun E, Ozgen IT, Gokce S, Aydin S, Cesur Y. Thyroid hormone levels in obese children and adolescents with non-alcoholic fatty liver disease. J Clin Res Pediatr Endocrinol. 2014;6(1):34-9. doi: 10.4274/Jcrpe.1155. [PubMed: 24637308]. [PubMed Central: PMC3986737].
  • 3. Wang CY, Chang TC, Chen MF. Associations between subclinical thyroid disease and metabolic syndrome. Endocr J. 2012;59(10):911-7. doi: 10.1507/endocrj.EJ12-0076. [PubMed: 22785370].
  • 4. Kc R, Khatiwada S, Deo Mehta K, Pandey P, Lamsal M, Majhi S. Cardiovascular risk factors in subclinical hypothyroidism: A case control study in nepalese population. J Thyroid Res. 2015;2015:305241. doi: 10.1155/2015/305241. [PubMed: 26523236]. [PubMed Central: PMC4615208].
  • 5. Manji N, Boelaert K, Sheppard MC, Holder RL, Gough SC, Franklyn JA. Lack of association between serum TSH or free T4 and body mass index in euthyroid subjects. Clin Endocrinol (Oxf). 2006;64(2):125-8. doi: 10.1111/j.1365-2265.2006.02433.x. [PubMed: 16430708].
  • 6. Sakurai M, Nakamura K, Miura K, Yoshita K, Takamura T, Nagasawa SY, et al. Association between a serum thyroid-stimulating hormone concentration within the normal range and indices of obesity in Japanese men and women. Intern Med. 2014;53(7):669-74. doi: 10.2169/internalmedicine.53.1387. [PubMed: 24694474].
  • 7. Nyrnes A, Jorde R, Sundsfjord J. Serum TSH is positively associated with BMI. Int J Obes (Lond). 2006;30(1):100-5. doi: 10.1038/sj.ijo.0803112. [PubMed: 16189501].
  • 8. Meng Z, Liu M, Zhang Q, Liu L, Song K, Tan J, et al. Gender and age impacts on the association between thyroid function and metabolic syndrome in Chinese. Medicine (Baltimore). 2015;94(50). e2193. doi: 10.1097/MD.0000000000002193. [PubMed: 26683929]. [PubMed Central: PMC5058901].
  • 9. Hastie T, Tibshirani R. Generalized additive models. Stat Sci. 1986;1(3):297-310. doi: 10.1214/ss/1177013604.
  • 10. Ihaka R, Gentleman R. R: A language for data analysis and graphics. J Comput Graph Stat. 1996;5(3):299-314. doi: 10.1080/10618600.1996.10474713.
  • 11. Svare A, Nilsen TI, Bjoro T, Asvold BO, Langhammer A. Serum TSH related to measures of body mass: Longitudinal data from the HUNT Study, Norway. Clin Endocrinol (Oxf). 2011;74(6):769-75. doi: 10.1111/j.1365-2265.2011.04009.x. [PubMed: 21521278].
  • 12. Kitahara CM, Platz EA, Ladenson PW, Mondul AM, Menke A, Berrington de Gonzalez A. Body fatness and markers of thyroid function among U.S. men and women. PLoS One. 2012;7(4). e34979. doi: 10.1371/journal.pone.0034979. [PubMed: 22511976]. [PubMed Central: PMC3325258].
  • 13. Kim B. Thyroid hormone as a determinant of energy expenditure and the basal metabolic rate. Thyroid. 2008;18(2):141-4. doi: 10.1089/thy.2007.0266. [PubMed: 18279014].
  • 14. Garcia-Solis P, Garcia OP, Hernandez-Puga G, Sanchez-Tusie AA, Saenz-Luna CE, Hernandez-Montiel HL, et al. Thyroid hormones and obesity: a known but poorly understood relationship. Endokrynol Pol. 2018;69(3):292-303. doi: 10.5603/EP.2018.0032. [PubMed: 29952420].
  • 15. Knudsen N, Laurberg P, Rasmussen LB, Bulow I, Perrild H, Ovesen L, et al. Small differences in thyroid function may be important for body mass index and the occurrence of obesity in the population. J Clin Endocrinol Metab. 2005;90(7):4019-24. doi: 10.1210/jc.2004-2225. [PubMed: 15870128].
  • 16. Betry C, Challan-Belval MA, Bernard A, Charrie A, Drai J, Laville M, et al. Increased TSH in obesity: Evidence for a BMI-independent association with leptin. Diabetes Metab. 2015;41(3):248-51. doi: 10.1016/j.diabet.2014.11.009. [PubMed: 25541439].
  • 17. Walrand S, Short KR, Heemstra LA, Novak CM, Levine JA, Coenen-Schimke JM, et al. Altered regulation of energy homeostasis in older rats in response to thyroid hormone administration. FASEB J. 2014;28(3):1499-510. doi: 10.1096/fj.13-239806. [PubMed: 24344330]. [PubMed Central: PMC3929673].
  • 18. Ortega E, Pannacciulli N, Bogardus C, Krakoff J. Plasma concentrations of free triiodothyronine predict weight change in euthyroid persons. Am J Clin Nutr. 2007;85(2):440-5. doi: 10.1093/ajcn/85.2.440. [PubMed: 17284741]. [PubMed Central: PMC1857361].
  • 19. Souza Ade M, Sichieri R. Relationship between body mass index and thyrotropin in euthyroid women: Differences by smoking, race and menopausal status. Obes Facts. 2011;4(2):175-9. doi: 10.1159/000327843. [PubMed: 21577025].
  • 20. Mehran L, Amouzegar A, Delshad H, Azizi F. Association between serum TSH concentration and body mass index in euthyroid subjects: The role of smoking. Arch Iran Med. 2012;15(7):400-3. [PubMed: 22724874].
  • 21. Chaker L, Korevaar TI, Medici M, Uitterlinden AG, Hofman A, Dehghan A, et al. Thyroid function characteristics and determinants: The rotterdam study. Thyroid. 2016;26(9):1195-204. doi: 10.1089/thy.2016.0133. [PubMed: 27484151].
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:

Author(s):

Article(s):

Create Citiation Alert
via Google Reader

Readers' Comments