Primary hypothyroidism: uncommon presentation with reversible dilated cardiomyopathy in a young subject


Sunil Kumar Kota 1 , * , Prabhas Ranjan 2 , Siva Krishna Kota 3 , Sruti Jammula 2 , Lalit Kumar Meher 2 , Kirtikumar Dharmshibhai Modi 4

1 Department of Endocrinology, Medwin Hospital, Hyderabad, [email protected], India

2 Department of Anatomy, Kalinga Institute of Medical Sciences, Bhubaneswar, India

3 Department of Anesthesia, Central Security Hospital, Saudi Arabia

4 Department of Endocrinology, Medwin Hospital, Hyderabad, India

How to Cite: Kota S, P, Kota S, Jammula S, Meher L, et al. Primary hypothyroidism: uncommon presentation with reversible dilated cardiomyopathy in a young subject, Int J Endocrinol Metab. Online ahead of Print ; 10(1):440-443. doi: 10.5812/ijem.2382.


International Journal of Endocrinology and Metabolism: 10 (1); 440-443
Article Type: Case Report
Received: September 25, 2011
Accepted: December 28, 2011




Most patients with dilated cardiomyopathy have a poor prognosis that is associated with progressive and irreversible myocardial dysfunction. Rarely, a reversible metabolic etiology that is amenable to specific therapy is identified. Thyroid hormones have many effects on the heart. Although cardiac output is reduced in hypothyroidism, heart failure is relatively rare due to the lower demand for peripheral oxygen delivery. We report a 14-year-old girl who presented with dilated cardiomyopathy (DCM) and was determined to have primary hypothyroidism, for whom cardiac function improved significantly after levothyroxine replacement therapy. Our case underscores the necessity of thyroid function testing to examine the etiology of nonischemic DCM, even in young subjects.

  • Implication for health policy/practice/research/medical education:
    Hypothyroidism is a rare cause of dilated cardiomyopathy and hormonal treatment with levothyroxine can significantly improve myocardial function. Hence it is felt that thyroid function tests should be systematically performed in all patients with DCM in order to rule out hypothyroidism.
  • Please cite this paper as:
    Kumar Kota S, Tripathy PR, Krishna Kota S, Jammula S, Kumar Meher L, Modi KD, Primary Hypothyroidism: Uncommon Presentation With Reversible Dilated Cardiomyopathy in a Young Subject. Int J Endocrinol Metab. 2012;10(1): 440-3. DOI: 10.5812/ijem.2382

                                                                      Copyright © 2012 Kowsar M. P. Co. All rights reserved.


Dilated Cardiomyopathy Hypothyroidism Levothyroxine

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