Advantage of Applying OSC to <sup>1</sup>H NMR-Based Metabonomic Data of Celiac Disease

Mostafa Rezaei-Tavirani; Fariba Fathi; Fatemeh Darvizeh; Mohamad Reza Reza Zali; Mohamad Rostami Rostami Nejad; Kamran Rostami; Mohsen Tafazzoli; Afsaneh Arefi Arefi oskouie; Seyed AbdolReza AbdolReza Mortazavi-Tabatabaei

doi:10.5812/ijem.3058

Advantage of Applying OSC to ¹H NMR-Based Metabonomic Data of Celiac Disease

Mostafa Rezaei-Tavirani ¹ , Fariba Fathi ² , Fatemeh Darvizeh ³ , Mohamad Reza Reza Zali ⁴ , Mohamad Rostami Rostami Nejad ⁵ , Kamran Rostami ⁶ , Mohsen Tafazzoli ^{2
, *} , Afsaneh Arefi Arefi oskouie ^{6
, *} and Seyed AbdolReza AbdolReza Mortazavi-Tabatabaei ⁶

Authors Information

¹ Proteomics Research Center, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, IR Iran

² Department of Chemistry, Sharif University of Technology, Tafazzoli@sharif.edu, IR Iran

³ Department of Medicine, Debrecen Medical School, Hungary

⁴ Research Center for Gastroenterology and Liver Disease, Shahid Beheshti University of Medical Sciences, IR Iran

⁵ Acute Medicine, Dudley Group of Hospital, UK

⁶ Department of Basic Science Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, a.arefi@sbmu.ir, IR Iran

Corresponding Authors:

Article information

International Journal of Endocrinology and Metabolism: , 10 (3); 548-552
Published Online: June 30, 2012
Article Type: Original Article
Received: November 2, 2011
Accepted: April 17, 2012
DOI: 10.5812/ijem.3058

To Cite: Rezaei-Tavirani M, Fathi F, Darvizeh F, Zali M R, Rostami Nejad M, et al. Advantage of Applying OSC to ¹H NMR-Based Metabonomic Data of Celiac Disease, Int J Endocrinol Metab. Online ahead of Print ;10(3):548-552. doi: 10.5812/ijem.3058.

Abstract

Patients and Methods: In this study, metabolites of total 56 serum samples from 12 CD patients, 15 CD patients taking gluten-free diet (GFD), and 29 healthy cases were analyzed using nuclear magnetic resonance (NMR) and associated theoretical analysis. Employing ProMetab (version ProMetab_v3_3) software, data obtained from NMR spectra were reduced and orthogonal signal correction (OSC) effect on celiac disease metabonomics before and after the separation by principle component analysis (PCA) was investigated.

© 2012, International Journal of Endocrinology and Metabolism. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

Full Text

Cited By:

Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:

Author(s):

Mostafa Rezaei-Tavirani: [PubMed] [Scholar]
Fariba Fathi: [PubMed] [Scholar]
Fatemeh Darvizeh: [PubMed] [Scholar]
Mohamad Reza Zali: [PubMed] [Scholar]
Mohamad Rostami Nejad: [PubMed] [Scholar]
Kamran Rostami: [PubMed] [Scholar]
Mohsen Tafazzoli: [PubMed] [Scholar]
Afsaneh Arefi oskouie: [PubMed] [Scholar]
Seyed AbdolReza Mortazavi-Tabatabaei: [PubMed] [Scholar]

Article(s):

Create Citiation Alert
via Google Reader