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Graves’ Ophthalmopathy: The Role of Thyroid Cross Reacting Autoantigens and The Effect of Thyroid Ablation

AUTHORS

F Latrofa 1 , M Marino 1 , C Marcocci 1 , A Pinchera 1 , *

AUTHORS INFORMATION

1 Department of Endocrinology and Metabolism, University Hospital of Pisa, Pisa, Italy

How to Cite: Latrofa F, Marino M, Marcocci C, Pinchera A. Graves’ Ophthalmopathy: The Role of Thyroid Cross Reacting Autoantigens and The Effect of Thyroid Ablation, Int J Endocrinol Metab. 2006 ; 4(1):e94592.

ARTICLE INFORMATION

International Journal of Endocrinology and Metabolism: 4 (1); e94592
Published Online: January 31, 2006
Article Type: Review Article
Received: May 28, 2019
Accepted: January 31, 2006

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Abstract

The pathogenesis and the treatment of Graves’ Ophthalmopathy (GO), the most common extrathyroidal mani
festation of Graves’ disease, are still debated [reviewed in1]. Although associated with Graves’ hyperthyroidism in most patients, GO may also occur with euthyroidism or hypothyroidism from Hashimoto’s thyroiditis (“euthyroid Graves’ disease”). GO precedes, occurs simultaneously with or follows hyperthyroidism in 13%, 43% and 44% of patients, respectively.2 The time interval between the beginning of GO and the onset of hyperthyroidism is <18 months in 85% of patients.

Keywords

Thyroid

© 2006, International Journal of Endocrinology and Metabolism. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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References

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