Non-Contraceptive Benefits of Oral Hormonal Contraceptives

AUTHORS

Adolf E Schindler 1 , *

1 Institute for Medical Research and Education, [email protected], Germany

How to Cite: Schindler A E. Non-Contraceptive Benefits of Oral Hormonal Contraceptives, Int J Endocrinol Metab. Online ahead of Print ; 11(1):41-47. doi: 10.5812/ijem.4158.

ARTICLE INFORMATION

International Journal of Endocrinology and Metabolism: 11 (1); 41-47
Published Online: December 21, 2012
Article Type: Review Article
Received: January 15, 2012
Accepted: June 23, 2012
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Abstract

Abstract: It is becoming evident that oral hormonal contraceptives besides being well established contraceptives seem to become important medications for many functional or organic disturbances. So far, clinical effectiveness has been shown for treatment as well as prevention of menstrual bleeding disorders and menstrual-related pain symptoms. Also this is true for premenstrual syndrome (PMS) and premenstrual disphoric disorder (PMDD).\r\nParticular oral contraceptives (OCs) containing anti-androgenic progestogens were shown to be effective medications for treatment of androgenisation symptoms (seborrhea, acne, hirsutism, alopecia).\r\nThrough perfect suppression of the hypothalamic-pituitary-ovarian axis OCs have proven to be effective in elimination of persistent follicular cysts. Endometriosis/adenomyosis related pain symptoms are well handled similar to other drugs like Gonadotropine Releasing Hormone agonists but are less expensive, with less side effects, and possibility to be used for longer periods of time. This is also true for myoma. Pelvic inflammatory disease, rheumatoid arthritis, menstrual migraine, and onset of multiple sclerosis are prevented or delayed. Bone density is preserved and asthma symptoms improved. Endometrial hyperplasia and benign breast disease can be controlled. There is definitely a significant impact on risk reduction regarding endometrial, ovarian, and colon cancers.\r\nIn conclusion, it needs to be recognized that oral combined hormonal contraceptives (estrogen/ progestogen combination) are besides being reliable forms of contraception are cost-effective medications for many medical disorders in women. Therefore, these contraceptives drugs are important for female and global health and should be used in clinical practice.

Keywords

Contraceptives Oral Hormonal Therapeutics Prevention and Control

© 2012, International Journal of Endocrinology and Metabolism. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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